Hydrochloric Acid → HCID 86732283, compound

Participants

Reaction Steps

To a solution of methyl 5-(oxazol-2-ylmethoxy)pyrazine-2-carboxylate (0.761 g, 3.23 mmol) in 1,4-dioxane (16.17 mL) was added sodium hydroxide 1.0N solution (3.23 ml, 3.23 mmol) to stir at room temperature for 16 h. Then HCl, 4.0M solution in 1,4-dioxane (1.617 ml, 6.47 mmol,) was added to stir for 10 min. The reaction mixture was concentrated in vacuo. MS m/z=221.9 [M+H]+. Calculated for C9H7N3O4: 221.044

Provenance & Evidence