N-[1-Benzyl-2-(1,5-dimethyl-6-oxo-1,6-dihydro-pyridin-3-yl)-1H-imidazo[4,5-c]pyridin-6-yl]-acetamide → 5-(6-Amino-1-benzyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,3-dimethyl-1H-pyridin-2-one

Participants

Reaction Conditions

Reaction Steps

N-[1-Benzyl-2-(1,5-dimethyl-6-oxo-1,6-dihydro-pyridin-3-yl)-1H-imidazo[4,5-c]pyridin-6-yl]-acetamide II-16′ (1.67 g; 4.315 mmol) is suspended in 6 N HCl. The reaction mixture is stirred for 1 h at 100° C. The reaction is then cooled to RT and quenched slowly with sodium bicarbonate, precipitation of the product occurs. The product is filtered off and dried under vacuum.

Provenance & Evidence