反应详情

温度

100 °C

N-[1-Benzyl-2-(1,5-dimethyl-6-oxo-1,6-dihydro-pyridin-3-yl)-1H-imidazo[4,5-c]pyridin-6-yl]-acetamide II-16′ (1.67 g; 4.315 mmol) is suspended in 6 N HCl. The reaction mixture is stirred for 1 h at 100° C. The reaction is then cooled to RT and quenched slowly with sodium bicarbonate, precipitation of the product occurs. The product is filtered off and dried under vacuum.

1. temperatureThe reaction is then cooled to RT
2. customquenched slowly with sodium bicarbonate, precipitation of the product
3. filtrationThe product is filtered off
4. customdried under vacuum