4-chloropyridine N-oxide → HCID 68658149, compound

HRID 930655Notes

Reaction equation

HRID 930655 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N+:5]([O-:8])=[CH:4][CH:3]=1.[Cl:9][C:10]1[CH:15]=[C:14]([Cl:16])[CH:13]=[CH:12][C:11]=1B(O)O>>[Cl:9][C:10]1[CH:15]=[C:14]([Cl:16])[CH:13]=[CH:12][C:11]=1[C:2]1[CH:7]=[CH:6][N+:5]([O-:8])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 707244-chloropyridine N-oxideHCID 2734659(2,4-Dichlorophenyl)boronic acid

Product 1

HCID 68658149HCID 68658149, compoundYield 50%

Procedure

4-Chloropyridine-N-oxide (1.5 g, 12 mmol), 2,4-dichlorophenylboronic acid (5.4 g, 29 mmol) were reacted according to the procedure of Example 39 (step a) to provide the title compound (1.40 g, 50%) as a grey solid: 1H NMR (500 MHz, CD3OD) δ 8.26 (d, J=6.9 Hz, 2H), 7.53 (d, J=2.0 Hz, 1H), 7.37-7.35 (m, 3H), 7.29 (d, J=8.3 Hz, 1H).

Sources & evidence

ORD record
ord-69901add863243558bc2b6ba5dfc7f40
Source dataset
uspto-grants-2016_03
Patent number
US09296743B2

Reaction notes

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