HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-(4-Chloro-3-(trifluoromethyl)phenoxy)-3-fluorophenyl)methanol → 8-((4-(4-chloro-3-(trifluoromethyl)phenoxy)-3-fluorobenzyl)oxy)-1-cyclopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-(4-Chloro-3-(trifluoromethyl)phenoxy)-3-fluorophenyl)methanol | HCID 71236627 | — |
| Reactant | 8-chloro-1-cyclopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one | HCID 90306570 | — |
| Product | 8-((4-(4-chloro-3-(trifluoromethyl)phenoxy)-3-fluorobenzyl)oxy)-1-cyclopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one | HCID 77107232 | — |
Reaction Steps
The title compound was prepared by a procedure similar to that described for E2 starting from 8-chloro-1-cyclopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one and (4-(4-chloro-3-(trifluoromethyl)phenoxy)-3-fluorophenyl)methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296755B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-d0265738dbfb4dc7ba0e868496885d67 |
| Source note | uspto-grants-2016_03 |