HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Chloro-3-(trifluoromethyl)phenoxy)-5-(hydroxymethyl)benzonitrile → 2-(4-chloro-3-(trifluoromethyl)phenoxy)-5-(((1-cyclopropyl-6-oxo-2,3,4,6-tetrahydro-1H-pyrimido[1,6-a]pyrimidin-8-yl)oxy)methyl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Chloro-3-(trifluoromethyl)phenoxy)-5-(hydroxymethyl)benzonitrile | HCID 66825608 | — |
| Reactant | 8-chloro-1-cyclopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one | HCID 90306570 | — |
| Product | 2-(4-chloro-3-(trifluoromethyl)phenoxy)-5-(((1-cyclopropyl-6-oxo-2,3,4,6-tetrahydro-1H-pyrimido[1,6-a]pyrimidin-8-yl)oxy)methyl)benzonitrile | HCID 77107235 | — |
Reaction Steps
The title compound was prepared by a procedure similar to that described for E2 starting from 8-chloro-1-cyclopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one and 2-(4-chloro-3-(trifluoromethyl) phenoxy)-5-(hydroxymethyl)benzonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296755B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-304d9b49488c49fbae57c7d188fee41a |
| Source note | uspto-grants-2016_03 |