HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Fluoro-4-(3-fluorophenoxy)phenyl)methanol → 1-cyclopropyl-8-((3-fluoro-4-(3-fluorophenoxy)benzyl)oxy)-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Fluoro-4-(3-fluorophenoxy)phenyl)methanol | HCID 28946122 | — |
| Reactant | 8-chloro-1-cyclopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one | HCID 90306570 | — |
| Product | 1-cyclopropyl-8-((3-fluoro-4-(3-fluorophenoxy)benzyl)oxy)-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one | HCID 77107236 | — |
Reaction Steps
The title compound was prepared by a procedure similar to that described for E2 starting from 8-chloro-1-cyclopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one and (3-fluoro-4-(3-fluorophenoxy)phenyl) methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296755B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-0a2de70dcd494fd0a59363f158ccf694 |
| Source note | uspto-grants-2016_03 |