HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4-Difluoropiperidine → 8-((3,4-difluorobenzyl)oxy)-1-(2-(4,4-difluoropiperidin-1-yl)-2-oxoethyl)-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4-Difluoropiperidine | HCID 2758352 | — |
| Reactant | HCID 90303921 | HCID 90303921 | — |
| Product | 8-((3,4-difluorobenzyl)oxy)-1-(2-(4,4-difluoropiperidin-1-yl)-2-oxoethyl)-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one | HCID 76853233 | — |
Reaction Steps
The title compound was prepared by a procedure similar to that described for E13 starting from 2-(8-((3,4-difluorobenzyl)oxy)-6-oxo-2,3,4,6-tetrahydro-1H-pyrimido[1,6-a]pyrimidin-1-yl)acetic acid and 4,4-difluoropiperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296755B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-b9bc6cf0208b400386c90a312e35dc98 |
| Source note | uspto-grants-2016_03 |