Propylamine → HCID 77107642, compound
Reaction equation
[O:1]=[C:2]1[N:7]2[CH2:8][CH2:9][CH2:10][N:11]([CH2:12][C:13](O)=[O:14])[C:6]2=[CH:5][C:4]([O:16][CH2:17][C:18]2[CH:23]=[C:22]([F:24])[C:21]([F:25])=[C:20]([F:26])[CH:19]=2)=[N:3]1.[CH2:27]([NH2:30])[CH2:28][CH3:29]>>[O:1]=[C:2]1[N:7]2[CH2:8][CH2:9][CH2:10][N:11]([CH2:12][C:13]([NH:30][CH2:27][CH2:28][CH3:29])=[O:14])[C:6]2=[CH:5][C:4]([O:16][CH2:17][C:18]2[CH:23]=[C:22]([F:24])[C:21]([F:25])=[C:20]([F:26])[CH:19]=2)=[N:3]1Participants
3
Procedure
The title compound was prepared by a procedure similar to that described for E13 starting from 2-(6-oxo-8-((3,4,5-trifluorobenzyl)oxy)-2,3,4,6-tetrahydro-1H-pyrimido[1,6-a]pyrimidin-1-yl) acetic acid and propan-1-amine.
Sources & evidence
- ORD record
- ord-1cb40222a35e493db56ecd1a323fffb3
- Source dataset
- uspto-grants-2016_03
- Patent number
- US09296755B2
Reaction notes
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