反应详情

The product from Example 311c (0.75 g, 1.979 mmol) and sodium thiomethoxide (0.139 g, 1.979 mmol) were combined in dimethylformamide (3.96 mL), stirred for 4 hours at ambient temperature, and partitioned into ethyl acetate and cold water. The organic layer was washed with saturated aqueous sodium chloride, dried (Na2SO4), filtered, and concentrated to afford the title compound (0.66 g, 96%).

1. custompartitioned into ethyl acetate and cold water
2. washThe organic layer was washed with saturated aqueous sodium chloride
3. dry with materialdried (Na2SO4)
4. filtrationfiltered
5. concentrationconcentrated