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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 930970Generated: October 31, 2026

2-Hydroxyisobutyric acid → HCID 90014556, compound

https://huagongshe.com/reaction/930970

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Hydroxyisobutyric acidHCID 11671—
ReactantHCID 90014477HCID 90014477—
ProductHCID 90014556HCID 90014556—

Reaction Steps

10 mg (130 μmol) (RS)-6-{[7-(aminomethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl]amino}-1,3-benzothiazol-2(3H)-one (prepared according to example 20) were transformed in analogy to example 23 using 2-hydroxy-2-methylpropanoic acid to give after working up and purification 23.8 mg (38%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296757B2
Source datasetuspto-grants-2016_03
ORD IDord-f048de1fa26c435599931b6d373210a7
Source noteuspto-grants-2016_03