反应详情

温度

50 °C

To a solution of 2,3-dichloro-5-(trifluoromethyl)pyridine (6.8 g) in ethanol (50 mL) was added hydrazine hydrate (3.15 g) in an ice bath, and the mixture was stirred overnight at 50° C. The mixture was allowed to be cooled to room temperature, and the solvent was evaporated under reduced pressure. The obtained residue was treated with IPE, and the precipitated solid was collected by filtration to give the title compound (7.57 g).

1. temperatureto be cooled to room temperature
2. customthe solvent was evaporated under reduced pressure
3. additionThe obtained residue was treated with IPE
4. filtrationthe precipitated solid was collected by filtration