Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 931099Generated: November 1, 2026

Trifluoroacetic acid → HCID 89853889, compound

https://huagongshe.com/reaction/931099

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 117966443HCID 117966443—
SolventDichloromethaneHCID 6344—
ProductHCID 89853889HCID 89853889100%

Reaction Steps

t-Butyl 3-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-3-yl)piperidine-1-carboxylate (65 mg, 0.1 mmol) was dissolved into a 20% trifluoroacetic acid in dichloromethane solution (2.4 mL). The reaction mixture was stirred at room temperature for 2.5 h. The solvent was removed under reduced pressure to afford 3-(piperidin-3-yl)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazole trifluoroacetate salt as an oil (94 mg, 100%). The material was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296745B2
Source datasetuspto-grants-2016_03
ORD IDord-c1cc411824fc4d73824e92787a8d9940
Source noteuspto-grants-2016_03