HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-cyclopropylpyrimidine-2-carbimidate → HCID 178521023, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-cyclopropylpyrimidine-2-carbimidate | HCID 89853794 | — |
| Reactant | (R)-(1-(5,6-diaminopyridin-2-yl)piperidin-3-yl)(morpholino)methanone dihydrochloride | HCID 89853875 | — |
| Reactant | (R)-(1-(5,6-Diaminopyridin-2-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone dihydrochloride | HCID 89854051 | — |
| Reactant | (R)-(1-(6-Amino-5-nitropyridin-2-yl)piperidin-3-yl)(morpholino)methanone | HCID 117966273 | — |
| Product | HCID 178521023 | HCID 178521023 | — |
Reaction Steps
The title compound was prepared by a method analogous to the one used for Example 95, but using (R)-(1-(5,6-diaminopyridin-2-yl)piperidin-3-yl)(morpholino)methanone dihydrochloride (synthesized by hydrogenation analogous to the one used for Intermediate 1, starting from Intermediate 40) and Intermediate 42. MS (ES+APCI) (M+H) 434.2; LCMS retention time 1.996 min (Method G).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296745B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-8130070eb213406ab6afc8a2e507cf95 |
| Source note | uspto-grants-2016_03 |