HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetaldehyde → HCID 178521024, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetaldehyde | HCID 998 | — |
| Reactant | (R)-(1-(6-amino-5-nitropyridin-2-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone | HCID 89853768 | — |
| Product | HCID 178521024 | HCID 178521024 | — |
Reaction Steps
(R)-(1-(2-Benzyl-3H-imidazo[4,5-b]pyridin-5-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone was prepared by a method analogous to the one used for Example 163, Step 1 at a temperature of 120° C. using (R)-(1-(6-amino-5-nitropyridin-2-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone and 2-phenylacetaldehyde. MS (ES+APCI) (M+H) 390.1; LCMS retention time 3.859 min (Method I).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296745B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-f82a6e4805fe4f058022ee8a5548f823 |
| Source note | uspto-grants-2016_03 |