Dichloromethane → Trifluoroacetic acid

HRID 93130Notes

Reaction equation

HRID 93130 reaction equation
[Cl:33][CH2:34][Cl:35].[F:26][C:27]([C:28](=[O:29])[OH:30])([F:31])[F:32].[O:1]=[c:2]1[nH:3][c:4](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:5][n:6]1[CH:7]1[CH2:8][CH2:9][N:10]([C:13]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:19])[CH2:11][CH2:12]1>>[F:26][C:27]([C:28](=[O:29])[OH:30])([F:31])[F:32].[O:1]=[c:2]1[nH:3][c:4](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:5][n:6]1[CH:7]1[CH2:8][CH2:9][NH:10][CH2:11][CH2:12]1

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 11653081tert-Butyl 4-(2-oxo-4-phenyl-2,3-dihydro-1H-imidazol-1-yl)piperidine-1-carboxylate

Product 2

HCID 6422Trifluoroacetic acidHCID 113455464-Phenyl-1-(piperidin-4-yl)-1,3-dihydro-2H-imidazol-2-one

Sources & evidence

ORD record
ord-b65d982841e544b997ecee0ac9f35803
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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