反应详情

温度

23 °C

Trifluoroacetic acid (21.7 mL, 283 mmol) was added to a solution of methyl 4-(3-(tert-butoxycarbonyl)but-3-en-2-yl)benzoate (8.7 g, 30 mmol) in anhydrous dichloromethane (85 mL), and the mixture was stirred at 23° C. for 5 h. The solvents were removed under reduced pressure and the residue was triturated with hexane. The solid was collected by filtration and dried under vacuo to give the title compound. MS: m/z=233.0 (M+1).

1. customThe solvents were removed under reduced pressure
2. customthe residue was triturated with hexane
3. filtrationThe solid was collected by filtration
4. customdried under vacuo