HCID 68277956, compound → HCID 68277995, compound

Participants

Reaction Steps

A solution of methyl 4-(5-methyl-4-((4-(morpholinomethyl)phenylsulfonyl)methyl)oxazol-2-yl)benzoate (1 g, 2.13 mmol, 1.00 equiv) in 6N hydrochloric acid (40 mL) was refluxed for 8 h. The reaction mixture was cooled to room temperature naturally and then diluted with 100 mL of water/ice. The precipitate was collected by filtration, washed with 2×20 mL of water and dried in a vacuum oven to give 0.7 g (72%) of 4-(5-methyl-4-((4-(morpholinomethyl)phenylsulfonyl)methyl)oxazol-2-yl)benzoic acid as a white solid.

Provenance & Evidence