Dichloromethane → 6-Methoxy-3-((pivaloyloxy)methyl)-7-(4-pyridylmethoxy)-3,4-dihydroquinazolin-4-one

HRID 93170Notes

Reaction equation

HRID 93170 reaction equation
[CH2:62]([Cl:63])[Cl:64].[O:1]=[C:2]([O:3][CH2:4][CH3:5])[N:6]=[N:7][C:8]([O:9][CH2:10][CH3:11])=[O:12].[OH:13][c:14]1[c:15]([O:33][CH3:34])[cH:16][c:17]2[c:18](=[O:32])[n:19]([CH2:24][O:25][C:26]([C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[cH:20][n:21][c:22]2[cH:23]1.[c:43]1([P:44]([c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[cH:57][cH:58][cH:59][cH:60][cH:61]1.[n:35]1[cH:36][cH:37][c:38]([CH2:41][OH:42])[cH:39][cH:40]1>>[O:13]([c:14]1[c:15]([O:33][CH3:34])[cH:16][c:17]2[c:18](=[O:32])[n:19]([CH2:24][O:25][C:26]([C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[cH:20][n:21][c:22]2[cH:23]1)[CH2:41][c:38]1[cH:37][cH:36][n:35][cH:40][cH:39]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 114724-HydroxymethylpyridineHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 10804576(7-Hydroxy-6-methoxy-4-oxoquinazolin-3(4H)-yl)methyl pivalate

Product 1

HCID 217172336-Methoxy-3-((pivaloyloxy)methyl)-7-(4-pyridylmethoxy)-3,4-dihydroquinazolin-4-one

Sources & evidence

ORD record
ord-7de530dfcbae462ab9cd8ca459a449ab
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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