HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-(5-bromo-2,7-dimethylquinolin-6-yl)-2-tert-butoxyethyl pivalate → (S)-2-(5-bromo-2,7-dimethylquinolin-6-yl)-2-tert-butoxyethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-(5-bromo-2,7-dimethylquinolin-6-yl)-2-tert-butoxyethyl pivalate | HCID 66630692 | — |
| Reactant | (S)-2-tert-butoxy-2-(7-chloro-5-(4-chlorophenyl)-2-methylquinolin-6-yl)ethanol | HCID 66631657 | — |
| Product | (S)-2-(5-bromo-2,7-dimethylquinolin-6-yl)-2-tert-butoxyethanol | HCID 66631978 | — |
Reaction Steps
Compound 5F was prepared following the procedure used to prepare compound 1K of Example 1, except that (S)-2-(5-bromo-2,7-dimethylquinolin-6-yl)-2-tert-butoxyethyl pivalate (5E) was used instead of compound 1J. LCMS-ESI+ (m/z): 352.2, 354.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296758B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-244efffbbc614a1c901de86dacb08646 |
| Source note | uspto-grants-2016_03 |