HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Chloro-2-methylquinolin-6-ol → 5-Bromo-7-methyl-2-(trifluoromethyl)quinolin-6-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Chloro-2-methylquinolin-6-ol | HCID 66631406 | — |
| Reactant | 5-Bromo-6-methoxy-7-methyl-2-(trifluoromethyl)quinoline | HCID 66631689 | — |
| Product | 5-Bromo-7-methyl-2-(trifluoromethyl)quinolin-6-ol | HCID 66631612 | — |
Reaction Steps
Compound 7B was prepared following the procedure used to prepare compound 1C of Example 1, except that 5-bromo-6-methoxy-7-methyl-2-(trifluoromethyl)quinoline (7A) was used instead of compound 1B. LCMS-ESI+ (m/z): 306.1, 308.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296758B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-b9f9f67cd380429ea1068343a7ebe504 |
| Source note | uspto-grants-2016_03 |