HRID932380

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID813

Potassium cation

K+

2 次

HCID13387

N-Methyl-2-pyrrolidone

C5H9NO

HCID19660

Carbonate

CO3-2

HCID10352036

4-Fluoro-5-hydroxy-2-methylindole

C9H8FNO

HCID10661998

7-(benzyloxy)-4-chloro-6-methoxyquinazoline

C16H13ClN2O2

PRODUCTS

产物

反应SMILES：COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCc1ccccc1

HCID10151204

7-(Benzyloxy)-4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinazoline

C25H20FN3O3

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-36423528756c4c04b9c1d4b8c1778abf
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应SMILES

[C:34](=[O:35])([O-:36])[O-:37].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:20][CH3:21])[cH:11][c:12]2[c:13]([Cl:19])[n:14][cH:15][n:16][c:17]2[cH:18]1.[CH3:40][N:41]1[CH2:42][CH2:43][CH2:44][C:45]1=[O:46].[F:22][c:23]1[c:24]2[cH:25][c:26]([CH3:33])[nH:27][c:28]2[cH:29][cH:30][c:31]1[OH:32].[K+:38].[K+:39]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:20][CH3:21])[cH:11][c:12]2[c:13]([O:32][c:31]3[c:23]([F:22])[c:24]4[cH:25][c:26]([CH3:33])[nH:27][c:28]4[cH:29][cH:30]3)[n:14][cH:15][n:16][c:17]2[cH:18]1