Dichloromethane → (4,4-Difluoro-azepan-1-yl)-(5-oxazol-4-yl-thiophen-3-yl)-methanone
Reaktionsgleichung
[CH2:63]1[O:64][CH2:65][CH2:66][CH2:67]1.[CH:30]([N:31]([CH2:32][CH3:33])[CH:34]([CH3:35])[CH3:36])([CH3:37])[CH3:38].[Cl:68][CH2:69][Cl:70].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[F:8][C:9]1([F:16])[CH2:10][CH2:11][NH:12][CH2:13][CH2:14][CH2:15]1.[P-:39]([F:40])([F:41])([F:42])([F:43])([F:44])[F:45].[n:46]1([O:47][C:48]([N:49]([CH3:50])[CH3:51])=[N+:52]([CH3:53])[CH3:54])[c:55]2[n:56][cH:57][cH:58][cH:59][c:60]2[n:61][n:62]1.[o:17]1[cH:18][n:19][c:20](-[c:22]2[cH:23][c:24]([C:27](=[O:28])[OH:29])[cH:25][s:26]2)[cH:21]1>>[F:8][C:9]1([F:16])[CH2:10][CH2:11][N:12]([C:27]([c:24]2[cH:23][c:22](-[c:20]3[n:19][cH:18][o:17][cH:21]3)[s:26][cH:25]2)=[O:28])[CH2:13][CH2:14][CH2:15]1Komponenten
9
Edukt 8
HCID 6344Dichloromethane
HCID 6422Trifluoroacetic acid
HCID 8028Tetrahydrofuran
HCID 9886Hexafluorophosphate
HCID 81531Diisopropylethylamine
HCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium
HCID 533934824,4-Difluoroazepane
HCID 581102215-Oxazol-4-yl-thiophene-3-carboxylic acidProdukt 1
Quellen und Nachweise
- ORD-Eintrag
- ord-4a4f130e9dc14864975a0d31b229a3be
- Quelldatensatz
- Validation data from https://doi.org/10.1039/C8SC04228D
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