Dimethylformamide → Methyl [4-bromo-2-(4-{[(1-ethylpropyl)amino]carbonyl}phenyl)thien-3-yl]acetate

HRID 932401Notes

Reaction equation

HRID 932401 reaction equation
[Br:1][c:2]1[c:3]([CH2:16][C:17](=[O:18])[O:19][CH3:20])[c:4](-[c:7]2[cH:8][cH:9][c:10]([C:11](=[O:12])[OH:13])[cH:14][cH:15]2)[s:5][cH:6]1.[NH2:21][CH:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31]>>[Br:1][c:2]1[c:3]([CH2:16][C:17](=[O:18])[O:19][CH3:20])[c:4](-[c:7]2[cH:8][cH:9][c:10]([C:11](=[O:13])[NH:21][CH:22]([CH2:23][CH3:24])[CH2:25][CH3:26])[cH:14][cH:15]2)[s:5][cH:6]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 120193-PentanamineHCID 692003654-(4-Bromo-3-methoxycarbonylmethyl-thiophen-2-yl)-benzoic acid

Product 1

HCID 86607182Methyl [4-bromo-2-(4-{[(1-ethylpropyl)amino]carbonyl}phenyl)thien-3-yl]acetate

Sources & evidence

ORD record
ord-52e786f21332498cacd421036f2d36d7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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