Water → N-[4-Chloro-2-(pyridine-3-carbonyl)phenyl]-2,2-dimethylpropanamide

HRID 932470Notes

Reaction equation

HRID 932470 reaction equation
[CH3:29][CH2:30][O:31][C:32]([CH3:33])=[O:34].[Cl:1][c:2]1[cH:3][c:4]([CH:15]([c:16]2[cH:17][n:18][cH:19][cH:20][cH:21]2)[OH:22])[c:5]([NH:8][C:9]([C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[cH:6][cH:7]1.[OH2:35].[cH:23]1[cH:24][cH:25][n:26][cH:27][cH:28]1>>[Cl:1][c:2]1[cH:3][c:4]([C:15]([c:16]2[cH:17][n:18][cH:19][cH:20][cH:21]2)=[O:22])[c:5]([NH:8][C:9]([C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 962WaterHCID 1049PyridineHCID 8857Ethyl AcetateHCID 22327296N-[4-chloro-2-(hydroxy-pyridin-3-yl-methyl)-phenyl]-2,2-dimethyl-propionamide

Product 1

HCID 14141153N-[4-Chloro-2-(pyridine-3-carbonyl)phenyl]-2,2-dimethylpropanamide

Sources & evidence

ORD record
ord-a05390a6238c40128ac489583a786fbe
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…