Dimethylformamide → ethyl 2-(4-acetyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-5-(methyl(2-phenoxyethyl)amino)thiazole-4-carboxylate

HRID 932530Notes

Reaction equation

HRID 932530 reaction equation
[C:1]([CH3:2])(=[O:3])[N:4]1[c:5]2[c:6]([cH:10][cH:11][c:12](-[c:14]3[s:15][c:16]([Cl:24])[c:17]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[n:18]3)[cH:13]2)[O:7][CH2:8][CH2:9]1.[CH3:25][NH:26][CH2:27][CH2:28][O:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[O:36]=[CH:37][N:38]([CH3:39])[CH3:40]>>[C:1]([CH3:2])(=[O:3])[N:4]1[c:5]2[c:6]([cH:10][cH:11][c:12](-[c:14]3[s:15][c:16]([N:26]([CH3:25])[CH2:27][CH2:28][O:29][c:30]4[cH:31][cH:32][cH:33][cH:34][cH:35]4)[c:17]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[n:18]3)[cH:13]2)[O:7][CH2:8][CH2:9]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 37732Methyl(2-phenoxyethyl)amineHCID 59418731ethyl 2-(4-acetyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-5-chlorothiazole-4-carboxylate

Product 1

HCID 59418712ethyl 2-(4-acetyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-5-(methyl(2-phenoxyethyl)amino)thiazole-4-carboxylate

Sources & evidence

ORD record
ord-351974a4f3fe42df9d0ff3470b109f43
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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