Ammonia → cis-4-(4-Amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-cyclohexanecarboxylic acid ethyl ester
Reaction equation
[CH2:2]([CH3:3])[O:4][C:5](=[O:6])[CH:7]1[CH2:8][CH2:9][CH:10]([n:13]2[cH:14][c:15]([I:23])[c:16]3[c:17]2[n:18][cH:19][n:20][c:21]3[Cl:22])[CH2:11][CH2:12]1.[CH:24]([OH:25])([CH3:26])[CH3:27].[NH3:1]>>[NH2:1][c:21]1[c:16]2[c:15]([I:23])[cH:14][n:13]([CH:10]3[CH2:9][CH2:8][CH:7]([C:5]([O:4][CH2:2][CH3:3])=[O:6])[CH2:12][CH2:11]3)[c:17]2[n:18][cH:19][n:20]1Participants
4
Sources & evidence
- ORD record
- ord-9a89832600d5496daf2cee9f3c3a00c2
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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