Chlorosuccinimide → 6-Chloro-3-(quinolin-3-yl)-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine
Reaction equation
[Br:1][c:2]1[c:3]([C:22]2=[CH:27][CH2:26][NH:25][CH2:24][CH2:23]2)[n:4][c:5]2[n:6]([c:7]1[NH2:8])[n:9][cH:10][c:11]2-[c:12]1[cH:13][n:14][c:15]2[cH:16][cH:17][cH:18][cH:19][c:20]2[cH:21]1.[Br:36][N:37]1[C:38](=[O:39])[CH2:40][CH2:41][C:42]1=[O:43].[Cl:28][N:29]1[C:30](=[O:31])[CH2:32][CH2:33][C:34]1=[O:35]>>[c:2]1([Cl:28])[c:3]([C:22]2=[CH:27][CH2:26][NH:25][CH2:24][CH2:23]2)[n:4][c:5]2[n:6]([c:7]1[NH2:8])[n:9][cH:10][c:11]2-[c:12]1[cH:13][n:14][c:15]2[cH:16][cH:17][cH:18][cH:19][c:20]2[cH:21]1Participants
4
Sources & evidence
- ORD record
- ord-08d5e863f1d441a2b873bbdd4737c56e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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