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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 932702Generated: October 30, 2026

Dimethylformamide → 4-Chloro-8-methoxy-2-(trifluoromethyl)quinoline

https://huagongshe.com/reaction/932702

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 178488807HCID 178488807—
Product4-Chloro-8-methoxy-2-(trifluoromethyl)quinolineHCID 621524—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-79cfe510f6fc444bb0585f095232d925
Source noteValidation data from https://doi.org/10.1039/C8SC04228D