Dimethylformamide → 4-Chloro-8-methoxy-2-(trifluoromethyl)quinoline
Reaction equation
[Cl:28][CH2:29][Cl:30].[O:18]=[CH:19][N:20]([CH3:21])[CH3:22].[OH:1][c:2]1[cH:3][c:4]([C:14]([F:15])([F:16])[F:17])[n:5][c:6]2[c:7]([O:12][CH3:13])[cH:8][cH:9][cH:10][c:11]12.[P:23]([Cl:24])([Cl:25])([Cl:26])=[O:27]>>[c:2]1([Cl:25])[cH:3][c:4]([C:14]([F:15])([F:16])[F:17])[n:5][c:6]2[c:7]([O:12][CH3:13])[cH:8][cH:9][cH:10][c:11]12Participants
5
Sources & evidence
- ORD record
- ord-79cfe510f6fc444bb0585f095232d925
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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