Acetic Acid → Propan-2-yl 4-[5-ethynyl-6-(2-fluoro-4-methylsulfonylphenoxy)pyrimidin-4-yl]oxypiperidine-1-carboxylate
Reaction equation
[C:40]([OH:41])(=[O:42])[CH3:43].[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:49][OH:50].[CH:1]([CH3:2])([CH3:3])[O:4][C:5](=[O:6])[N:7]1[CH2:8][CH2:9][CH:10]([O:13][c:14]2[n:15][cH:16][n:17][c:18]([O:26][c:27]3[c:28]([F:37])[cH:29][c:30]([S:33](=[O:34])(=[O:35])[CH3:36])[cH:31][cH:32]3)[c:19]2[C:20]#[C:21][Si:22]([CH3:23])([CH3:24])[CH3:25])[CH2:11][CH2:12]1.[Na+:39].[OH-:38]>>[CH:1]([CH3:2])([CH3:3])[O:4][C:5](=[O:6])[N:7]1[CH2:8][CH2:9][CH:10]([O:13][c:14]2[n:15][cH:16][n:17][c:18]([O:26][c:27]3[c:28]([F:37])[cH:29][c:30]([S:33](=[O:34])(=[O:35])[CH3:36])[cH:31][cH:32]3)[c:19]2[C:20]#[CH:21])[CH2:11][CH2:12]1Participants
7
Sources & evidence
- ORD record
- ord-fd5e8c7ca5cc40d985e40aa1e5813ba9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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