Dichloromethane → 1-(3-{4-[(Pyrrolidin-1-yl)methyl]phenoxy}cyclobutyl)methanamine
Reaction equation
[Cl:34][CH2:35][Cl:36].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[N:8]1([CH2:13][c:14]2[cH:15][cH:16][c:17]([O:18][CH:19]3[CH2:20][CH:21]([CH2:23][NH:24][C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:22]3)[cH:32][cH:33]2)[CH2:9][CH2:10][CH2:11][CH2:12]1>>[N:8]1([CH2:13][c:14]2[cH:15][cH:16][c:17]([O:18][CH:19]3[CH2:20][CH:21]([CH2:23][NH2:24])[CH2:22]3)[cH:32][cH:33]2)[CH2:9][CH2:10][CH2:11][CH2:12]1Participants
4
Sources & evidence
- ORD record
- ord-6f0c85d7955d4a47aaefb9444b6f0f91
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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