Methanol → [2-(2-Amino-5-methoxyphenyl)-ethyl]-(1-benzylpiperidin-4-yl)-amine

HRID 932810Notes

Reaction equation

HRID 932810 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][CH2:15][CH2:16][c:17]2[c:18]([N+:25]([O-:26])=[O:27])[cH:19][cH:20][c:21]([O:23][CH3:24])[cH:22]2)[CH2:12][CH2:13]1.[CH3:31][OH:32].[H:29][H:30].[OH2:28].[Rh:33]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][CH2:15][CH2:16][c:17]2[c:18]([NH2:25])[cH:19][cH:20][c:21]([O:23][CH3:24])[cH:22]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 887MethanolHCID 962WaterHCID 23948RhodiumHCID 21109931(1-Benzylpiperidin-4-yl)-[2-(5-methoxy-2-nitrophenyl)-ethyl]-amineHCID 178418361HCID 178418361, compound

Product 1

HCID 59626805[2-(2-Amino-5-methoxyphenyl)-ethyl]-(1-benzylpiperidin-4-yl)-amine

Sources & evidence

ORD record
ord-73290b51038e4ccaab8aa84d5a33a645
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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