Dichloromethane → 3-{2-Cyclohexylcarbamoyloxymethyl-4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxy]phenyl}propionic acid
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][CH2:8][c:9]1[c:10]([CH2:30][O:31][C:32]([NH:33][CH:34]2[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39]2)=[O:40])[cH:11][c:12]([O:15][CH2:16][CH2:17][c:18]2[n:19][c:20](-[c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[o:21][c:22]2[CH3:23])[cH:13][cH:14]1)=[O:41].[Cl:49][CH2:50][Cl:51].[OH:42][C:43]([C:44]([F:45])([F:46])[F:47])=[O:48]>>[O:5]=[C:6]([CH2:7][CH2:8][c:9]1[c:10]([CH2:30][O:31][C:32]([NH:33][CH:34]2[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39]2)=[O:40])[cH:11][c:12]([O:15][CH2:16][CH2:17][c:18]2[n:19][c:20](-[c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[o:21][c:22]2[CH3:23])[cH:13][cH:14]1)[OH:41]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-8236e7a89a1b4de7bad665bba1356aa7
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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