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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 932963Generated: October 27, 2026

Tetrahydrofuran → Tert-butyl 3-[1-[2-(cyclopropylmethoxy)-3-fluorophenyl]-1-hydroxy-5-methoxypentyl]piperidine-1-carboxylate

https://huagongshe.com/reaction/932963

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant1-Chloro-4-methoxybutaneHCID 87363—
ReactantMagnesiumHCID 5462224—
ReactantTert-butyl 3-[2-(cyclopropylmethoxy)-3-fluorobenzoyl]piperidine-1-carboxylateHCID 67193895—
ProductTert-butyl 3-[1-[2-(cyclopropylmethoxy)-3-fluorophenyl]-1-hydroxy-5-methoxypentyl]piperidine-1-carboxylateHCID 72283045—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-b68039a6a2564c94a43af87af283c57d
Source noteValidation data from https://doi.org/10.1039/C8SC04228D