Tetrahydrofuran → Tert-butyl 3-[1-[2-(cyclopropylmethoxy)-3-fluorophenyl]-1-hydroxy-5-methoxypentyl]piperidine-1-carboxylate

HRID 932963Notes

Reaction equation

[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH:9]1([CH2:12][O:13][c:14]2[c:15]([C:16](=[O:17])[CH:18]3[CH2:19][N:20]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:21][CH2:22][CH2:23]3)[cH:31][cH:32][cH:33][c:34]2[F:35])[CH2:10][CH2:11]1.[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][O:6][CH3:7].[Mg:8]>>[CH2:2]([CH2:3][CH2:4][CH2:5][O:6][CH3:7])[C:16]([c:15]1[c:14]([O:13][CH2:12][CH:9]2[CH2:10][CH2:11]2)[c:34]([F:35])[cH:33][cH:32][cH:31]1)([OH:17])[CH:18]1[CH2:19][N:20]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:21][CH2:22][CH2:23]1