Toluene → 4,6-Dichloropicolinaldehyde

HRID 933029Notes

Reaction equation

[C:1](=[O:2])([O:3][CH3:4])[c:5]1[n:6][c:7]([Cl:12])[cH:8][c:9]([Cl:11])[cH:10]1.[CH3:13][CH:14]([CH2:15][AlH:16][CH2:17][CH:18]([CH3:19])[CH3:20])[CH3:21].[CH3:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1>>[CH:1](=[O:2])[c:5]1[n:6][c:7]([Cl:12])[cH:8][c:9]([Cl:11])[cH:10]1

Participants

Reactant 3

HCID 1140Toluene

HCID 14487Diisobutylaluminum hydride

HCID 18922464Methyl 4,6-dichloropyridine-2-carboxylate

Product 1

HCID 147957044,6-Dichloropicolinaldehyde

Sources & evidence

ORD record: ord-def9092789184f6f952bc54bbb0ee16c
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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