Sodium ion → 3-Chloro-5-(difluoromethoxy)benzoic acid

HRID 933088Notes

Reaction equation

[CH:18]([Cl:19])([Cl:20])[Cl:21].[Cl:14][CH:15]([F:16])[F:17].[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[cH:8][c:9]([OH:11])[cH:10]1.[Na+:13].[OH-:12]>>[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[cH:8][c:9]([O:11][CH:15]([F:16])[F:17])[cH:10]1

Participants

Reactant 5

HCID 923Sodium ion

HCID 961Hydroxide

HCID 6212Chloroform

HCID 6372Chlorodifluoromethane

HCID 130716463-Chloro-5-hydroxybenzoic Acid

Product 1

HCID 219046063-Chloro-5-(difluoromethoxy)benzoic acid

Sources & evidence

ORD record: ord-374d3950e37f40ab9e0339d7c268a959
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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