Water → Methyl 2-(3-hydroxypyrrolidin-1-yl)-1,3-thiazole-5-carboxylate
Reaction equation
[Br:1][c:2]1[s:3][c:4]([C:7](=[O:8])[O:9][CH3:10])[cH:5][n:6]1.[CH2:17]1[CH2:18][CH2:19][C:20]2=[N:25][CH2:24][CH2:23][CH2:22][N:21]2[CH2:26][CH2:27]1.[NH:11]1[CH2:12][CH:13]([OH:16])[CH2:14][CH2:15]1.[O:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1.[OH2:34]>>[c:2]1([N:11]2[CH2:12][CH:13]([OH:16])[CH2:14][CH2:15]2)[s:3][c:4]([C:7](=[O:8])[O:9][CH3:10])[cH:5][n:6]1Participants
6
Sources & evidence
- ORD record
- ord-998668e42ad04991a22a16ec27f81afb
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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