Acetic Acid → N-(o-(2,2,2-Trifluoroethoxy)phenyl)-4-piperidone
Reaction equation
[CH2:1]1[O:2][C:5]2([O:4][CH:3]1[CH3:23])[CH2:6][CH2:7][N:8]([c:11]1[c:12]([O:17][CH2:18][C:19]([F:20])([F:21])[F:22])[cH:13][cH:14][cH:15][cH:16]1)[CH2:9][CH2:10]2.[CH3:25][C:26](=[O:27])[OH:28].[ClH:24].[OH2:29]>>[O:4]=[C:5]1[CH2:6][CH2:7][N:8]([c:11]2[c:12]([O:17][CH2:18][C:19]([F:20])([F:21])[F:22])[cH:13][cH:14][cH:15][cH:16]2)[CH2:9][CH2:10]1Participants
5
Sources & evidence
- ORD record
- ord-9b14f4b0241d4e1b87a4f638e5fb8953
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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