Dimethylformamide → [2-(benzyloxy)-5-(5H-pyrrolo[3,2-d]pyrimidin-4-ylamino)phenyl]methanol

HRID 933155Notes

Reaction equation

HRID 933155 reaction equation
[CH3:28][N:29]([CH3:30])[CH:31]=[O:32].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][cH:9][nH:10]2.[NH2:11][c:12]1[cH:13][cH:14][c:15]([O:20][CH2:21][c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[c:16]([CH2:18][OH:19])[cH:17]1>>[c:2]1([NH:11][c:12]2[cH:13][cH:14][c:15]([O:20][CH2:21][c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[c:16]([CH2:18][OH:19])[cH:17]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][cH:9][nH:10]2

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 53706954-chloro-5H-pyrrolo[3,2-d]pyrimidineHCID 219043564-Benzyloxy-3-hydroxymethylaniline

Product 1

HCID 57597321[2-(benzyloxy)-5-(5H-pyrrolo[3,2-d]pyrimidin-4-ylamino)phenyl]methanol

Sources & evidence

ORD record
ord-c69d856eed564dc18dda6629bb604f0c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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