Trifluoroacetic acid → 1-(2-Pyrimidinyl)piperazine
Reaction equation
[F:25][C:26]([F:27])([F:28])[C:29]([OH:30])=[O:31].[N+:1]([c:2]1[cH:3][cH:4][c:5]([O:6][C:7]([NH:8][c:9]2[s:10][c:11](-[c:12]3[cH:13][cH:14][cH:15][cH:16][cH:17]3)[cH:18][n:19]2)=[O:20])[cH:21][cH:22]1)([O-:23])=[O:24].[c:32]1(-[c:33]2[s:34][c:35]([NH:36][C:37]([NH:38][N:47]3[CH2:48][CH2:49][N:50]([c:53]4[n:54][cH:55][cH:56][cH:57][n:58]4)[CH2:51][CH2:52]3)=[O:39])[n:40][cH:41]2)[cH:42][cH:43][cH:44][cH:45][cH:46]1>>[NH:47]1[CH2:48][CH2:49][N:50]([c:53]2[n:54][cH:55][cH:56][cH:57][n:58]2)[CH2:51][CH2:52]1Participants
4
Sources & evidence
- ORD record
- ord-c4ba85d6ece64bf481033787dd7a720f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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