Methanol → 4-[2-(3,3,5,5-Tetramethylcyclohexyl)phenyl]piperazine-1-carboxylic acid t-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]([C:20]3=[CH:21][C:22]([CH3:28])([CH3:29])[CH2:23][C:24]([CH3:26])([CH3:27])[CH2:25]3)[cH:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1.[CH3:30][OH:31].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]([CH:20]3[CH2:21][C:22]([CH3:28])([CH3:29])[CH2:23][C:24]([CH3:26])([CH3:27])[CH2:25]3)[cH:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1Participants
4
Sources & evidence
- ORD record
- ord-b0ab72ec9da949b8abf91bd5d94d8a9c
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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