Dichloromethane → 2,4-Difluoro-N-(2-hydroxy-1,1-dimethylethyl)benzamide

HRID 933367Notes

Reaction equation

HRID 933367 reaction equation
[CH2:28]([Cl:29])[Cl:30].[F:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][c:9]([F:11])[cH:10]1.[NH2:12][C:13]([CH2:14][OH:15])([CH3:16])[CH3:17].[OH:18][n:19]1[c:20]2[c:21]([cH:22][cH:23][cH:24][cH:25]2)[n:26][n:27]1>>[F:1][c:2]1[c:3]([C:4](=[O:6])[NH:12][C:13]([CH2:14][OH:15])([CH3:16])[CH3:17])[cH:7][cH:8][c:9]([F:11])[cH:10]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 118072-Amino-2-methyl-1-propanolHCID 741022,4-Difluorobenzoic acidHCID 757711-Hydroxybenzotriazole

Product 1

HCID 98374972,4-Difluoro-N-(2-hydroxy-1,1-dimethylethyl)benzamide

Sources & evidence

ORD record
ord-8f440866a5824f7ab1ca7e344983982e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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