Bicarbonate Ion → (4-Methylmorpholin-3-yl)methyl 4-(4-fluorophenyl)piperazine-1-carboxylate

HRID 933598Notes

Reaction equation

HRID 933598 reaction equation
[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:3][N:4]1[CH:5]([CH2:10][OH:11])[CH2:6][O:7][CH2:8][CH2:9]1.[H-:2].[N+:12]([c:13]1[cH:14][cH:15][c:16]([O:21][C:22](=[O:17])[N:24]2[CH2:25][CH2:26][N:27]([c:30]3[cH:31][cH:32][c:33]([F:36])[cH:34][cH:35]3)[CH2:28][CH2:29]2)[cH:18][cH:19]1)([O-:20])=[O:23].[Na+:1].[Na+:41].[O-:37][C:38]([OH:39])=[O:40]>>[CH3:3][N:4]1[CH:5]([CH2:10][O:11][C:22](=[O:21])[N:24]2[CH2:25][CH2:26][N:27]([c:30]3[cH:31][cH:32][c:33]([F:36])[cH:34][cH:35]3)[CH2:28][CH2:29]2)[CH2:6][O:7][CH2:8][CH2:9]1

Participants

7

Reactant 6

HCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 8028TetrahydrofuranHCID 166653HydrideHCID 23541157(4-Methylmorpholin-3-yl)methanolHCID 595944824-(4-Fluorophenyl)-piperazine-1-carboxylic acid 4-nitrophenyl ester

Product 1

HCID 42634519(4-Methylmorpholin-3-yl)methyl 4-(4-fluorophenyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-a284d67306084674bc7865966c02d694
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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