Dichloromethane → N-(4-amino-5-methyl-3-oxohexyl)-2,2-dichloro-N-(2-(3-(2,6-dichlorophenyl)isoxazol-5-yl)pyridin-4-yl)acetamide
Reaction equation
[CH2:49]([Cl:50])[Cl:51].[Cl:8][CH:9]([C:10](=[O:11])[N:12]([c:13]1[cH:14][c:15](-[c:19]2[cH:20][c:21](-[c:24]3[c:25]([Cl:31])[cH:26][cH:27][cH:28][c:29]3[Cl:30])[n:22][o:23]2)[n:16][cH:17][cH:18]1)[CH2:32][CH2:33][C:34]([CH:35]([CH:36]([CH3:37])[CH3:38])[NH:39][C:40](=[O:41])[O:42][C:43]([CH3:44])([CH3:45])[CH3:46])=[O:47])[Cl:48].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[Cl:8][CH:9]([C:10](=[O:11])[N:12]([c:13]1[cH:14][c:15](-[c:19]2[cH:20][c:21](-[c:24]3[c:25]([Cl:31])[cH:26][cH:27][cH:28][c:29]3[Cl:30])[n:22][o:23]2)[n:16][cH:17][cH:18]1)[CH2:32][CH2:33][C:34]([CH:35]([CH:36]([CH3:37])[CH3:38])[NH2:39])=[O:47])[Cl:48]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-41ba2957cad641868872ff3f73ee0b07
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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