Imidazole → 3-((Tert-butyldimethylsilyl)oxy)-6-fluoro-1-indanone
Reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[Si:17]([CH3:18])([CH3:19])[Cl:20].[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[OH:1][CH:2]1[CH2:3][C:4](=[O:12])[c:5]2[cH:6][c:7]([F:11])[cH:8][cH:9][c:10]21.[nH:21]1[cH:22][cH:23][n:24][cH:25]1>>[O:1]([CH:2]1[CH2:3][C:4](=[O:12])[c:5]2[cH:6][c:7]([F:11])[cH:8][cH:9][c:10]21)[Si:17]([C:13]([CH3:14])([CH3:15])[CH3:16])([CH3:18])[CH3:19]Participants
5
Sources & evidence
- ORD record
- ord-faa9cbed11cd4bc6a7ebe4630f6035e0
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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