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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 933820Generated: October 25, 2026

2-Chloro-4-(2-(trimethylsilyl)ethynyl)pyridine → 2-Chloro-4-[2-methyl-1-(2,2,2-trifluoro-ethyl)-1H-imidazol-4-ylethynyl]-pyridine

https://huagongshe.com/reaction/933820

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-(2-(trimethylsilyl)ethynyl)pyridineHCID 21985391—
Reactant4-Iodo-2-methyl-1-(2,2,2-trifluoroethyl)-1H-imidazoleHCID 21985398—
Product2-Chloro-4-[2-methyl-1-(2,2,2-trifluoro-ethyl)-1H-imidazol-4-ylethynyl]-pyridineHCID 11472091—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-4ffc21e3b1db4e9ab4a19ec132a15dbd
Source noteValidation data from https://doi.org/10.1039/C8SC04228D