Ethyl Acetate → 8-amino-2-(4-tert-butyl-phenyl)-3,4-dihydro-2H-isoquinolin-1-one

HRID 933832Notes

Reaction equation

HRID 933832 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([N:11]2[C:12](=[O:24])[c:13]3[c:14]([N+:21]([O-:22])=[O:23])[cH:15][cH:16][cH:17][c:18]3[CH2:19][CH2:20]2)[cH:9][cH:10]1.[CH3:25][CH2:26][O:27][C:28]([CH3:29])=[O:30]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([N:11]2[C:12](=[O:24])[c:13]3[c:14]([NH2:21])[cH:15][cH:16][cH:17][c:18]3[CH2:19][CH2:20]2)[cH:9][cH:10]1

Participants

3

Reactant 2

HCID 8857Ethyl AcetateHCID 691594242-(4-tert-butyl-phenyl)-8-nitro-3,4-dihydro-2H-isoquinolin-1-one

Product 1

HCID 691593468-amino-2-(4-tert-butyl-phenyl)-3,4-dihydro-2H-isoquinolin-1-one

Sources & evidence

ORD record
ord-7152c47e2f47454f92eab07490fd22e3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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