Tetrahydrofuran → 4-[3-(4-Tert-butylaminocarbonylphenyl)-3-hydroxyprop-1-yl]-1-tritylimidazole

HRID 933954Notes

Reaction equation

[Br:6][c:7]1[cH:8][cH:9][c:10]([C:11](=[O:12])[NH:13][C:14]([CH3:15])([CH3:16])[CH3:17])[cH:18][cH:19]1.[C:20]([c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)([c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1)([c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[n:39]1[cH:40][n:41][c:42]([CH2:44][CH2:45][CH:46]=[O:47])[cH:43]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:48][CH2:49][CH2:50][CH2:51][CH2:52][CH3:53].[O:54]1[CH2:55][CH2:56][CH2:57][CH2:58]1>>[c:7]1([CH:46]([CH2:45][CH2:44][c:42]2[n:41][cH:40][n:39]([C:20]([c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)([c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[c:33]3[cH:34][cH:35][cH:36][cH:37][cH:38]3)[cH:43]2)[OH:47])[cH:8][cH:9][c:10]([C:11](=[O:12])[NH:13][C:14]([CH3:15])([CH3:16])[CH3:17])[cH:18][cH:19]1